Aryana Libris

Author : Cooper Raymond
Title : Botanical medicine from bench to bedside
Year : 2009

Link download : Cooper_Raymond_-_Botanical_medicine_from_bench_to_bedside.zip

Forword. The editors have produced a valuable book that will serve the broad community of researchers who seek to conduct scientifi cally sound research on botanicals used for medicinal purposes. The content evolved from an American Society of Pharmacognosy workshop titled “Clinical Pharmacognosy: Contribution of Pharmacognosy to Clinical Trials of Botanicals and Dietary Supplements” and highlights some of the best quality research, the complexities of studying botanical extracts, and potential pitfalls and challenges of searching for active compounds. The book contains authoritative chapters, ranging from how to ensure quality products through to clinical aspects of widely used and emerging botanical medicines. The topics and par tic u lar botanicals chosen are illustrative of the detailed examination and knowledge needed to take an herb from the fi eld to the phytochemistry laboratory, to a clinically useful product. It is important, given signifi cant marketing spin in product advertising, labels, and Internet sites, that the book as a compilation, enables the reader to see the links between the extracting methods, the design of basic scientifi c studies, and the questions asked in a clinical trial, based on scientifi c rationale, as well as documented use. Data are succinctly presented and include multicomponent interactions; detailed pharmacology; mechanisms of action, safety and toxicology; and exemplify issues to take into consideration when conducting research or reading scientifi c papers on botanicals. Or ga nized into three sections— selection and quality of botanical preparations, preclinical and clinical approaches, and a practitioner’s view of the challenges for those interested in exploring botanical preparations— this book is, to the best of my knowledge, the fi rst to address all three of these subject areas under the same cover. This book enables clinical researchers to appreciate the unique challenges of researching herbal products, and basic scientists and developers of the fi nal products to be cognizant of what is relevant to clinicians who seek to guide patients on the choice and use of herbal products. It is important to understand the biological activity for a par tic u lar indication, which would lead to more informed and productive clinical trials. This approach will facilitate the development of effective dosing and should reduce the ambiguity created by multiple clinical trials of the “same” product with different intended outcomes. This book is valuable for anyone seeking to understand the intricacies of researching botanical medicines. More than twenty scientifi c contributors have prepared chapters based on their own expertise and experience, or from detailed analyses of the literature. The editors, Drs. Ray Cooper and Fredi Kronenberg, should be congratulated for bringing together such a diverse group of contributors with such high expertise with the goal of facilitating high- quality botanical research. Norman R. Farnsworth, Ph.D.. ...